Paulo Dybala has fully recovered from a low-grade left thigh injury and is aiming to start against Inter.
He could seize the opportunity to score his 200th career goal.
La Joya is ahead of Pellegrini, completing an all-Argentine midfield alongside Soulé.
Another doubt concerns the left flank. As Il Tempo reports, Angelino appears likely to miss due to asthmatic bronchitis, which forced him to train in the gym yesterday.
His replacement could be Rensch, who trained at Trigoria throughout the international break, in contrast to Tsimikas, who has been less consistent.
This move could also serve to curb the physical exuberance of his compatriot Dumfries.
For the second day in a row, Bailey is training with the group. Against Inter, he is likely to start on the bench for the first time since joining the Giallorossi, hoping to get his first minutes for Roma.