Roma suffered a tough blow yesterday when VIllar and Cristante tested positive for COVID-19.
According to Il Tempo, the two players are expected to follow a mandatory quarantine period of at least 10 days before testing again.
Upon their return from Genova, the rest of the team will undergo a strict home-work-home protocol for the next seven days.
In the meantime, Mourinho will have to come up with a plan B or plan C for tonight as Cristante was to start in the defense with Villar potentially slotting in the midfield.